Description

Haloprotac 2 CAS NO 1799506-06-1 is a high-purity, advanced small molecule PROTAC (PROteolysis TArgeting Chimera) degrader. This compound is specifically designed for targeted protein degradation research, offering a powerful tool for investigating novel therapeutic pathways and validating drug targets. It is essential for pharmaceutical R&D, biotechnology, and academic laboratories focused on oncology, neurodegenerative diseases, and other areas of targeted protein degradation.

Application

• Targeted Protein Degradation Research: A core tool for studying PROTAC-mediated ubiquitination and proteasomal degradation of specific target proteins.
• Drug Discovery & Validation: Used in hit-to-lead optimization and as a pharmacological probe to validate novel targets in disease models.
• Oncology Research: Investigation of degrading oncoproteins and other cancer-related targets for potential therapeutic development.
• Chemical Biology Studies: Employed to understand protein function, signaling pathways, and cellular processes through induced protein knockdown.
• Biomarker Discovery: Aiding in the identification of downstream effects and biomarkers associated with target protein loss.
• Academic & Institutional Research: Fundamental research in universities and research institutes exploring the mechanisms and applications of PROTAC technology.

Basic Information

Product Name	Haloprotac 2
CAS No.	1799506-06-1
Molecular Formula	C44H53ClN6O7S
Molecular Weight	845.44 g/mol
Synonyms	Haloprotac-2; Haloprotac2; (S,R,S)-AHPC-PEG4-C6-VHL Ligand 2; VHL Ligand-Linker Conjugates 2; VH 032-PEG4-C6-Cl; PROTAC VHL Ligand 2; (S,R,S)-AHPC-PEG4-C6-Cl; E3 ligase ligand-linker conjugate for PROTAC
EINECS	Contact for details

Quality Control

Our Haloprotac 2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.