Description

(S)-n-[1-(Aminocarbonyl)Propyl]-4-Chlorobutanamide-D3 is a deuterated, isotopically labeled derivative of a chiral amino acid derivative, distinguished by the substitution of three hydrogen atoms with deuterium. This compound matters for its critical role as a high-purity internal standard and reference material in quantitative analytical methods, particularly Liquid Chromatography-Mass Spectrometry (LC-MS). Pharmaceutical, agrochemical, and contract research organizations need it to ensure the accuracy, precision, and regulatory compliance of their bioanalytical studies, pharmacokinetic research, and metabolic pathway investigations.

Application

• Primary use as a stable isotope-labeled internal standard for the precise quantification of its non-deuterated counterpart in complex biological matrices via LC-MS/MS.
• Critical reference material in pharmacokinetic (PK) and pharmacodynamic (PD) studies to track drug absorption, distribution, metabolism, and excretion (ADME).
• Essential tool in metabolite identification and profiling within drug discovery and development pipelines.
• Used in clinical research and diagnostic assay development requiring high specificity and sensitivity.
• Application in environmental fate studies for tracing agrochemicals and their degradation products.
• Valuable for academic research involving chiral synthesis, isotopic labeling techniques, and mechanistic biochemical studies.

Basic Information

Product Name	(S)-n-[1-(Aminocarbonyl)Propyl]-4-Chlorobutanamide-D3
CAS No.	1795786-85-4
Molecular Formula	C8H11D3ClN2O2
Molecular Weight	214.69 g/mol (for deuterated form)
Synonyms	(S)-N-[1-(Aminocarbonyl)Propyl]-4-Chlorobutanamide-d3; 4-Chloro-N-[(2S)-1-amino-1-oxobutan-2-yl]butanamide-d3; Deuterated (S)-4-Chloro-N-(1-carbamoylpropyl)butyramide; (S)-4-Chloro-N-(1-carbamoylpropyl)butyramide-d3; Isotopically Labeled Chiral Butyramide Derivative; Internal Standard for LC-MS; Chiral Deuterated Reference Standard
EINECS	Contact for details

Quality Control

Every batch of (S)-n-[1-(Aminocarbonyl)Propyl]-4-Chlorobutanamide-D3 is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, with comprehensive characterization using NMR (¹H, ¹³C), Mass Spectrometry (MS), and High-Performance Liquid Chromatography (HPLC). Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, isotopic enrichment, and all analytical results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98 atom % D
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.