Description

n-[4-[[(4,6-Dimethyl-2-Pyrimidinyl)Amino]Sulfonyl]Phenyl-D4]-3-(5-Nitro-2-Thienyl)-2-Propenamide is a deuterated, high-purity chemical intermediate designed for advanced research and development. This compound is critical for applications requiring stable isotope labeling, such as in the synthesis of internal standards for mass spectrometry. It is primarily utilized by pharmaceutical R&D teams and analytical laboratories working on drug metabolism, pharmacokinetic studies, and proteomics.

Application

• Deuterated Internal Standard Synthesis for precise quantitative analysis in Liquid Chromatography-Mass Spectrometry (LC-MS).
• Pharmaceutical Research & Development, particularly in the study of drug metabolism and pharmacokinetics (DMPK).
• Proteomics and Biomarker Discovery, where stable isotope-labeled compounds are used for accurate relative and absolute quantification.
• Chemical Biology Studies to trace molecular pathways and mechanisms of action.
• Advanced Material Science research involving specialty polymers or organic electronic materials.
• Contract Research Organization (CRO) Services supporting drug discovery and development pipelines.

Basic Information

Product Name	n-[4-[[(4,6-Dimethyl-2-Pyrimidinyl)Amino]Sulfonyl]Phenyl-D4]-3-(5-Nitro-2-Thienyl)-2-Propenamide
CAS No.	1795138-17-8
Molecular Formula	C19H15D4N5O5S2
Molecular Weight	465.55 g/mol
Synonyms	Deuterated Sulfonyl Pyrimidine Propenamide; 3-(5-Nitro-2-thienyl)-N-[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl-d4]-2-propenamide; N-[4-[[(4,6-Dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl-d4]-3-(5-nitro-2-thienyl)acrylamide; 1795138-17-8; Deuterated Sulfonamide Intermediate; D4-Labeled Sulfonylurea Derivative; Stable Isotope Labeled Compound; Deuterated Acrylamide Derivative
EINECS	Contact for details

Quality Control

Every batch of n-[4-[[(4,6-Dimethyl-2-Pyrimidinyl)Amino]Sulfonyl]Phenyl-D4]-3-(5-Nitro-2-Thienyl)-2-Propenamide is manufactured under strict quality management systems. We guarantee high chemical purity and isotopic enrichment, with comprehensive testing including HPLC for chemical purity and NMR/MS for deuterium incorporation verification. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Incorporation (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.