Description

5-Chloro-2-Hydroxy-Benzoic Acid Methyl Ester-13C,D3 is a stable isotope-labeled derivative of methyl salicylate, specifically enriched with carbon-13 and deuterium. This compound is essential as a high-purity internal standard for precise quantitative analysis in mass spectrometry, ensuring accurate and reliable measurement results. It is primarily required by analytical laboratories, contract research organizations (CROs), and pharmaceutical companies engaged in advanced method development, pharmacokinetic studies, and metabolite identification.

Application

• Used as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the quantification of related compounds in complex matrices.
• Critical for pharmaceutical research and development, particularly in bioanalytical assays for drug metabolism and pharmacokinetics (DMPK) studies.
• Enables accurate analysis in environmental testing for tracing pollutants or degradation products derived from salicylate esters.
• Supports forensic and clinical toxicology laboratories in the precise identification and measurement of specific analytes.
• Facilitates academic research in organic chemistry and biochemistry involving isotopic labeling and tracer studies.
• Applicable in quality control processes within chemical manufacturing to monitor the purity and consistency of related active pharmaceutical ingredients (APIs).

Basic Information

Product Name	5-Chloro-2-Hydroxy-Benzoic Acid Methyl Ester-13C,D3
CAS No.	1794756-19-6
Molecular Formula	C7H2D3Cl13CO3
Molecular Weight	~174.59 g/mol
Synonyms	Methyl 5-Chlorosalicylate-13C,D3; 5-Chloro-2-hydroxybenzoic-13C acid methyl-d3 ester; Methyl 5-chloro-2-hydroxybenzoate-13C,d3; 13C,D3-Labeled Methyl 5-Chlorosalicylate; 5-Chloro-2-hydroxybenzoic acid methyl ester (carbon-13C, methyl-d3); 2-Hydroxy-5-chlorobenzoic acid methyl ester-13C,D3
EINECS	Contact for details

Quality Control

Our stable isotope-labeled products are manufactured under controlled conditions to ensure exceptional chemical and isotopic purity. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and MS, to confirm identity, purity, and isotopic enrichment. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity	≥99 atom % 13C; ≥98 atom % D
Chemical Purity	≥95%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.