Description

3-(Trifluoromethyl)Cyclobutanol is a versatile fluorinated cyclobutane derivative, a key building block prized for its unique structural and electronic properties. Its value lies in introducing the metabolically stable and lipophilic trifluoromethyl group into complex molecular architectures, significantly altering physicochemical profiles. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it serves as a critical intermediate in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial synthon for developing new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the CF3 group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated into specialty polymers to impart unique characteristics such as chemical resistance, thermal stability, and modified surface properties.
• Organic Synthesis & Catalysis: Acts as a valuable scaffold in asymmetric synthesis and as a ligand precursor in organometallic catalysis.
• Fluorine Chemistry Research: A key material for academic and industrial research exploring new reactions and properties of fluorinated alicyclic compounds.

Basic Information

Product Name	3-(Trifluoromethyl)Cyclobutanol
CAS No.	1788054-83-0
Molecular Formula	C5H7F3O
Molecular Weight	140.11 g/mol
Synonyms	3-(Trifluoromethyl)cyclobutan-1-ol; Cyclobutanol, 3-(trifluoromethyl)-; 3-Trifluoromethylcyclobutanol; 1-Cyclobutanol, 3-(trifluoromethyl)-; 3-(Trifluoromethyl)-1-cyclobutanol; 3-(Trifluoromethyl)cyclobutyl alcohol; 3-CF3-Cyclobutanol
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Cyclobutanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its nature as a fluoride/strong alkali reactive and highly volatile compound, keep away from heat, sparks, and incompatible materials. Keep the container tightly sealed when not in use to prevent evaporation and moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.