Description

(R)-Cr8 (Trihydrochloride) is a high-purity, chiral chemical compound of significant interest in advanced pharmaceutical research and development. Its primary value lies in its role as a key intermediate or active pharmaceutical ingredient (API) for targeted therapies, where stereochemical purity is critical for efficacy and safety. This product is essential for research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in the synthesis of novel drug candidates, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex, chiral active pharmaceutical ingredients (APIs).
• Preclinical & Clinical Research: Used in drug discovery and development programs to study mechanism of action, pharmacokinetics, and therapeutic potential.
• Reference Standard: Employed as a high-purity analytical standard for method development, validation, and quality control testing of drug substances and products.
• Chemical Biology Probes: Utilized in academic and industrial research to investigate specific biological pathways and protein interactions.
• Process Chemistry Development: Supports scale-up and optimization of synthetic routes for commercial manufacturing.

Basic Information

Product Name	(R)-Cr8 (Trihydrochloride)
CAS No.	1786438-30-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(R)-Cr8 trihydrochloride; CR8, (R)-isomer, trihydrochloride; (R)-CR8 HCl; (R)-CR8 hydrochloride; (R)-CR8 tri-HCl; (R)-Cyclin-dependent kinase inhibitor CR8 trihydrochloride; (R)-Seliciclib trihydrochloride analog
EINECS	Contact for details

Quality Control

Our (R)-Cr8 (Trihydrochloride) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.