Description

(2-(Difluoromethyl)Pyridin-3-Yl)Methanol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a difluoromethyl group and a hydroxymethyl substituent on the pyridine ring, makes it an essential intermediate for creating novel compounds with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance bioavailability and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of specialty polymers and liquid crystals, where fluorinated aromatic units impart specific electronic and physical characteristics.
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags and molecular probes to study biological processes.

Basic Information

Product Name	(2-(Difluoromethyl)Pyridin-3-Yl)Methanol
CAS No.	1784521-24-9
Molecular Formula	C7H7F2NO
Molecular Weight	159.13 g/mol
Synonyms	3-(Hydroxymethyl)-2-(difluoromethyl)pyridine; 2-(Difluoromethyl)-3-pyridinemethanol; (2-Difluoromethyl-pyridin-3-yl)-methanol; 3-Pyridinemethanol, 2-(difluoromethyl)-; 2-(Difluoromethyl)-3-(hydroxymethyl)pyridine; 2-Difluoromethyl-3-hydroxymethylpyridine; 2-(Difluoromethyl)nicotinyl alcohol
EINECS	Contact for details

Quality Control

Our (2-(Difluoromethyl)Pyridin-3-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming identity, assay, and impurity profiles. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Any individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.