Description

2-Bromo-3-Chloro-4-Fluoro-1-Methylbenzene is a high-purity, multi-halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials that require precise halogen functionality.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Precursor: Serves as a monomer or functionalization agent for creating specialty polymers, liquid crystals, and electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and structure-activity relationship (SAR) studies.
• Fluorine Chemistry: The presence of the fluorine atom makes it a valuable substrate for further fluorination reactions and the development of fluorinated bioactive compounds.

Basic Information

Item	Details
Product Name	2-Bromo-3-Chloro-4-Fluoro-1-Methylbenzene
CAS No.	1783823-53-9
Molecular Formula	C7H5BrClF
Molecular Weight	223.47 g/mol
Synonyms	1-Bromo-2-chloro-3-fluoro-4-methylbenzene; 3-Chloro-2-bromo-4-fluorotoluene; 4-Fluoro-3-chloro-2-bromotoluene; 2-Bromo-3-chloro-4-fluorotoluene; Toluene, 2-bromo-3-chloro-4-fluoro-; 1783823-53-9
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Chloro-4-Fluoro-1-Methylbenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.