Description

7-(Difluoromethyl)-1,2,3,4-Tetrahydroquinoline (Wxc01614) is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because the difluoromethyl group is a key bioisostere, offering unique electronic and metabolic properties that are highly valuable in modern pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules. Its specific structure makes it a versatile intermediate for constructing complex, fluorine-containing target compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research where fluorination enhances bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the difluoromethyl group to improve efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty chemicals and advanced materials, including liquid crystals and organic electronic components.
• Chemical Biology & Proteomics: Employed as a probe or tag in medicinal chemistry for studying enzyme interactions and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.
• Academic Research: Used in university and institutional laboratories for methodological development and exploration of new fluorination chemistry.

Basic Information

Product Name	7-(Difluoromethyl)-1,2,3,4-Tetrahydroquinoline (Wxc01614)
CAS No.	1783624-20-3
Molecular Formula	C10H11F2N
Molecular Weight	183.20 g/mol
Synonyms	7-(Difluoromethyl)-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-7-(difluoromethyl)quinoline; WXC01614; Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-; 1783624-20-3; DFM-Tetrahydroquinoline; 7-DFM-THQ
EINECS	Contact for details

Quality Control

Every batch of 7-(Difluoromethyl)-1,2,3,4-Tetrahydroquinoline is produced under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong alkalis and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.