Description

2-Bromo-4,6-Difluorotoluene is a halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials who require high-purity, reliable synthetic precursors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing difluoromethyl or aryl bromide motifs for further functionalization.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the bromine and fluorine substituents impart specific biological activity and stability.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) to form biaryl structures.
• Fluorine Chemistry Studies: An important compound for investigating structure-activity relationships (SAR) and the effects of fluorine substitution in medicinal and agrochemistry.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and verification.

Basic Information

Item	Details
Product Name	2-Bromo-4,6-Difluorotoluene
CAS No.	1783551-12-1
Molecular Formula	C7H5BrF2
Molecular Weight	207.02 g/mol
Synonyms	1-Bromo-3,5-difluoro-2-methylbenzene; 3,5-Difluoro-2-methylbromobenzene; 2-Methyl-3,5-difluorobromobenzene; Toluene, 2-bromo-4,6-difluoro-; 4,6-Difluoro-2-bromotoluene; 2-Bromo-4,6-difluoromethylbenzene
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4,6-Difluorotoluene is produced and tested under a strict quality management system. We ensure high chemical purity and consistency through advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.