Description

1-Bromo-5-Fluoroethylbenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents on an ethylbenzene core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) to form new carbon-carbon bonds.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating specialized chemical libraries.
• Fluorine Chemistry Studies: A valuable substrate for investigating the unique electronic and steric effects of fluorine in aromatic systems.

Basic Information

Product Name	1-Bromo-5-Fluoroethylbenzene
CAS No.	1781676-21-8
Molecular Formula	C8H8BrF
Molecular Weight	203.05 g/mol
Synonyms	5-Bromo-2-fluoroethylbenzene; 2-Fluoro-5-bromoethylbenzene; 1-Bromo-5-fluoroethylbenzene; 1-Ethyl-4-bromo-2-fluorobenzene; 4-Bromo-2-fluoroethylbenzene; (4-Bromo-2-fluorophenyl)ethane; Ethyl-4-bromo-2-fluorobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-5-Fluoroethylbenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.45 g/cm³
Boiling Point	~210-215°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.