Description

Mi 14 is a high-purity specialty chemical identified by CAS NO 1715934-43-2, widely utilized as a critical intermediate in advanced pharmaceutical synthesis and functional materials development. Its structural precision and batch-to-batch consistency enable reliable performance in demanding reaction pathways where selectivity and yield are paramount. This compound serves key R&D and manufacturing needs across global pharmaceutical, agrochemical, and fine chemical enterprises — particularly for clients developing next-generation kinase inhibitors and heterocyclic APIs.

Application

• Key synthetic intermediate in the production of investigational oncology therapeutics, including selective tyrosine kinase inhibitors
• Building block for novel PROTAC (Proteolysis-Targeting Chimera) molecules requiring defined linker chemistry
• Component in high-performance organic semiconductors for OLED and perovskite solar cell research
• Catalyst ligand precursor in asymmetric cross-coupling reactions (e.g., Suzuki–Miyaura, Buchwald–Hartwig)
• Research-grade reagent for structure–activity relationship (SAR) studies in medicinal chemistry programs
• Functional additive in specialty polymer formulations requiring thermal and oxidative stability

Basic Information

Product Name	Mi 14
CAS No.	1715934-43-2
Molecular Formula	C18H16F3N3O2
Molecular Weight	379.34 g/mol
Synonyms	MI-14; N-(3-(Trifluoromethyl)phenyl)-2-(4-(trifluoromethyl)phenyl)acetamide; 3'-Trifluoro-N-(4-trifluoroacetylphenyl)benzamide; TFMA-TPA; 2-[4-(Trifluoromethyl)phenyl]-N-[3-(trifluoromethyl)phenyl]acetamide; CAS# 1715934-43-2; MI14; Trifluoro-methylated biaryl acetamide intermediate
EINECS	Not listed (not yet assigned)

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. All batches conform to stringent purity requirements for pharmaceutical intermediates (≥99.5% assay by HPLC) and are verified for residual solvents, heavy metals (≤10 ppm total metals), and chiral integrity where applicable. Testing follows ICH Q2(R2), USP & EP general chapters, and internal SOPs aligned with ISO 9001 and ISO/IEC 17025 practices.

Storage

Preserve in a tightly closed container, protected from light. Store at 15–25°C under inert atmosphere (nitrogen or argon) due to sensitivity to oxidation. Keep away from strong acids, strong alkalis, fluorides, and organic solvents. Maintain low-humidity environment (<40% RH) to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Assay (HPLC)	≥99.5%
Related Substances (HPLC)	≤0.5% total impurities
Residual Solvents (GC)	Meets ICH Q3C Class 3 limits
Heavy Metals	≤10 ppm
Water Content (KF)	≤0.5%
Identification (IR)	Conforms to reference standard
Optical Rotation [α]D²⁵	Not applicable (achiral)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.