Description

4-Fluoro-5-Iodo-Pyridin-2-Ylamine is a high-purity, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Functional Material Development: Employed in the research and production of advanced electronic materials and organic semiconductors.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	4-Fluoro-5-Iodo-Pyridin-2-Ylamine
CAS No.	1708974-12-2
Molecular Formula	C5H4FIN2
Molecular Weight	237.99 g/mol
Synonyms	2-Amino-4-fluoro-5-iodopyridine; 5-Iodo-4-fluoropyridin-2-amine; 4-Fluoro-5-iodo-2-pyridinamine; 4-Fluoro-5-iodopyridin-2-amine; 2-Pyridinamine, 4-fluoro-5-iodo-; 4-Fluoro-5-iodo-2-aminopyridine; 1708974-12-2
EINECS	Contact for details

Quality Control

Our 4-Fluoro-5-Iodo-Pyridin-2-Ylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates, from research to commercial-scale cGMP production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and stored away from direct light and moisture sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.