Description

4-Fluoropyridin-3-Amine Dihydrochloride is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized, halogenated amine scaffold essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the research of advanced organic electronic materials and liquid crystals due to its conjugated pyridine core.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	4-Fluoropyridin-3-Amine Dihydrochloride
CAS No.	1707365-31-8
Molecular Formula	C5H7Cl2FN2
Molecular Weight	185.03 g/mol
Synonyms	3-Amino-4-fluoropyridine dihydrochloride; 4-Fluoro-3-pyridinamine dihydrochloride; 4-Fluoropyridin-3-ylamine dihydrochloride; 4-Fluoro-3-aminopyridine dihydrochloride; 3-Pyridinamine, 4-fluoro-, dihydrochloride; 1707365-31-8; 4-Fluoro-3-aminopyridine hydrochloride (1:2)
EINECS	Contact for details

Quality Control

Our 4-Fluoropyridin-3-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.