Description

1-(3-Fluoropyridin-4-Yl)Piperazine Trihydrochloride is a high-purity, advanced pharmaceutical intermediate and building block of significant interest in modern medicinal chemistry. Its core value lies in its role as a key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. This compound is essential for R&D chemists, process development scientists, and manufacturers in the pharmaceutical and biotechnology sectors seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to optimize lead compounds.
• API Synthesis: Serves as a key precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• CNS Drug Development: Particularly valuable for researching compounds that interact with neurotransmitter systems, such as antipsychotics or antidepressants.
• Oncology Research: Employed in the development of kinase inhibitors and other targeted cancer therapies.
• Chemical Biology Probes: Used to create tool compounds for studying biological processes and target validation.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and pilot-scale manufacturing of clinical trial materials.
• Contract Research & Manufacturing (CRO/CMO): A reliable raw material for organizations providing custom synthesis and development services.

Basic Information

Product Name	1-(3-Fluoropyridin-4-Yl)Piperazine Trihydrochloride
CAS No.	1707358-41-5
Molecular Formula	C9H13F N4 • 3HCl
Molecular Weight	Contact for details
Synonyms	1-(3-Fluoropyridin-4-yl)piperazine trihydrochloride; 4-(3-Fluoropyridin-4-yl)piperazine trihydrochloride; 1-(3-Fluoro-4-pyridinyl)piperazine trihydrochloride; 3-Fluoro-4-(piperazin-1-yl)pyridine trihydrochloride; 1-(3-Fluoropyridin-4-yl)piperazine hydrochloride (1:3); Piperazine, 1-(3-fluoro-4-pyridinyl)-, trihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(3-Fluoropyridin-4-Yl)Piperazine Trihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.