Description

2-Fluoro-4-(Pentafluorosulfur)Benzenesulfonyl Chloride is a high-value, multi-functional organofluorine building block. Its unique structure, featuring both a sulfonyl chloride and a pentafluorosulfur group, makes it a critical intermediate for introducing specific fluorinated motifs into target molecules. This compound is essential for researchers and manufacturers in advanced chemical synthesis, particularly in the development of novel active ingredients. Its primary utility lies in constructing complex molecules for pharmaceuticals, agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially in the development of sulfonamide-based drugs and fluorinated therapeutics.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides that benefit from enhanced bioavailability and stability from fluorine incorporation.
• Material Science: Serves as a precursor for creating specialty polymers, liquid crystals, and advanced materials with tailored surface properties and chemical resistance.
• Chemical Research: A versatile reagent in organic synthesis for constructing complex fluorinated aromatic systems and introducing the pentafluorosulfanyl (SF5) group, a "super-trifluoromethyl" group.
• Ligand and Catalyst Development: Employed in the design of novel ligands and catalysts for transition metal catalysis, leveraging the unique electronic properties of the SF5 group.

Basic Information

Product Name	2-Fluoro-4-(Pentafluorosulfur)Benzenesulfonyl Chloride
CAS No.	1706462-71-6
Molecular Formula	C6H2ClF6O2S2
Molecular Weight	316.66 g/mol
Synonyms	2-Fluoro-4-(pentafluoro-λ6-sulfanyl)benzenesulfonyl chloride; 4-SF5-2-Fluorobenzenesulfonyl chloride; 1-Fluoro-4-(pentafluorosulfanyl)benzene-2-sulfonyl chloride; Benzenesulfonyl chloride, 2-fluoro-4-(pentafluorosulfanyl)-; SF5-Aromatic sulfonyl chloride; (2-Fluoro-4-(SF5)phenyl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(Pentafluorosulfur)Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our quality commitment ensures material consistency and reliability for your sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.