Description

2-Methyl-5-(Pentafluorosulfur)Benzenesulfonylchloride is a high-value, specialty organosulfur compound featuring a unique pentafluorosulfur (SF5) substituent. This advanced chemical intermediate is critical for introducing the highly lipophilic and electron-withdrawing SF5 group into target molecules, enabling the development of novel materials and bioactive compounds. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating next-generation products with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new drug candidates.
• Agrochemical Research: Used in the development of advanced herbicides, fungicides, and insecticides where the SF5 group can improve metabolic stability and bioavailability.
• Functional Material Synthesis: Serves as a precursor for creating specialty polymers, liquid crystals, and electronic materials with unique dielectric or surface properties.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological systems and mechanisms of action.
• Cross-Coupling Reactions: Acts as a versatile electrophile in palladium-catalyzed and other cross-coupling reactions to form complex biaryl structures.
• Sulfonamide Library Synthesis: A crucial reagent for generating diverse sulfonamide libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	2-Methyl-5-(Pentafluorosulfur)Benzenesulfonylchloride
CAS No.	1706458-82-3
Molecular Formula	C7H6ClF5O2S2
Molecular Weight	316.69 g/mol
Synonyms	5-(Pentafluoro-λ6-sulfanyl)-2-methylbenzenesulfonyl chloride; 2-Methyl-5-(pentafluorosulfanyl)benzenesulfonyl chloride; 2-Methyl-5-SF5-benzenesulfonyl chloride; 1-Methyl-4-(pentafluorosulfanyl)benzene-2-sulfonyl chloride; 4-Methyl-3-sulfonylchloride-pentafluorosulfanylbenzene; SF5-Aryl Sulfonyl Chloride Intermediate; Benzenesulfonyl chloride, 2-methyl-5-(pentafluorosulfanyl)-
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Pentafluorosulfur)Benzenesulfonylchloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques including NMR, HPLC, and GC-MS for comprehensive characterization and purity verification. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, amines, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.