Description

2,4-Difluoro-3-Methoxybenzenesulfonylchloride is a high-purity, specialized sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile sulfonylation reagent, enabling the introduction of the 2,4-difluoro-3-methoxybenzenesulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluoro-methoxy substitution pattern can confer specific biological activity.
• Material Science Research: Employed in the development of specialty polymers and functional materials that require sulfonamide linkages or specific aromatic fluorination patterns.
• Chemical Biology Probes: Serves as a reagent for modifying proteins or creating activity-based probes in biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2,4-Difluoro-3-Methoxybenzenesulfonylchloride
CAS No.	1706458-65-2
Molecular Formula	C7H5ClF2O3S
Molecular Weight	242.63 g/mol
Synonyms	2,4-Difluoro-3-methoxybenzenesulfonyl chloride; 3-Methoxy-2,4-difluorobenzenesulfonyl chloride; Benzenesulfonyl chloride, 2,4-difluoro-3-methoxy-; 2,4-Difluoro-3-methoxybenzene-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-3-Methoxybenzenesulfonylchloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.