Description

3-Chloro-2-Fluoro-5-(Trifluoromethyl)Benzenesulfonylchloride is a high-value, multi-functional aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its dual reactive sites, enabling the introduction of both the sulfonamide group and the unique halogenated aryl scaffold into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor for the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Used in the development of specialty polymers, liquid crystals, and advanced electronic materials.
• Chemical Biology: Employed as a reactive handle for bioconjugation and the development of chemical probes.
• Custom Synthesis & Contract Manufacturing: A versatile starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Chloro-2-Fluoro-5-(Trifluoromethyl)Benzenesulfonylchloride
CAS No.	1706458-27-6
Molecular Formula	C7H2Cl2F4O2S
Molecular Weight	313.06 g/mol
Synonyms	3-Chloro-2-fluoro-5-(trifluoromethyl)benzenesulfonyl chloride; 2-Fluoro-3-chloro-α,α,α-trifluoro-5-toluenesulfonyl chloride; 2-Fluoro-3-chloro-5-(trifluoromethyl)benzenesulfonyl chloride; 5-(Trifluoromethyl)-3-chloro-2-fluorobenzenesulfonyl chloride; Benzenesulfonyl chloride, 3-chloro-2-fluoro-5-(trifluoromethyl)-; 3-Chloro-2-fluoro-5-trifluoromethylbenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluoro-5-(Trifluoromethyl)Benzenesulfonylchloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.