Description

3-Chloro-5-Fluoro-4-Methoxybenzenesulfonylchloride is a high-purity, multi-functional sulfonyl chloride intermediate of significant importance in advanced organic synthesis. Its core value lies in its reactive sulfonyl chloride group, which enables the efficient introduction of the corresponding sulfonamide or sulfonate moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a critical building block for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated methoxybenzene structure for bioactivity.
• Material Science Research: Employed in the creation of specialized polymers and functional materials where the sulfonyl group imparts specific chemical or physical properties.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling or modifying biomolecules in research applications.
• Dye and Pigment Manufacturing: Serves as an intermediate in the synthesis of complex colorants and specialty dyes.

Basic Information

Product Name	3-Chloro-5-Fluoro-4-Methoxybenzenesulfonylchloride
CAS No.	1706458-23-2
Molecular Formula	C7H5Cl2FO3S
Molecular Weight	283.08 g/mol
Synonyms	3-Chloro-5-fluoro-4-methoxybenzenesulfonyl chloride; 4-Methoxy-3-chloro-5-fluorobenzenesulfonyl chloride; Benzenesulfonyl chloride, 3-chloro-5-fluoro-4-methoxy-; 3-Chloro-5-fluoro-4-methoxybenzene-1-sulfonyl chloride; CAS 1706458-23-2; 3-Cl-5-F-4-MeO-Benzenesulfonyl Chloride
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluoro-4-Methoxybenzenesulfonylchloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.