Description

2,6-Difluoro-3-Methoxybenzenesulfonylchloride is a high-purity, specialized sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its value lies in its unique difluoro-methoxy substitution pattern, which enables the precise introduction of a reactive sulfonyl chloride group into complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of new active ingredients and fine chemicals requiring specific fluorine-containing motifs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that benefit from fluorine's metabolic stability.
• Material Science Research: Serves as a monomer or modifying agent in the development of specialty polymers and advanced materials.
• Chemical Biology Probes: Employed in the creation of activity-based probes and other tools for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2,6-Difluoro-3-Methoxybenzenesulfonylchloride
CAS No.	1706458-18-5
Molecular Formula	C7H5ClF2O3S
Molecular Weight	242.63 g/mol
Synonyms	2,6-Difluoro-3-methoxybenzenesulfonyl chloride; 3-Methoxy-2,6-difluorobenzenesulfonyl chloride; 2,6-Difluoro-3-methoxybenzene-1-sulfonyl chloride; 1-(Chlorosulfonyl)-2,6-difluoro-3-methoxybenzene; Benzenesulfonyl chloride, 2,6-difluoro-3-methoxy-; 1706458-18-5; 2,6-Difluoro-3-methoxy phenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2,6-Difluoro-3-Methoxybenzenesulfonylchloride is manufactured and tested under strict quality management systems. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and GC, is performed to verify identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request and with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.