Description

3-Fluoro-4-Methyl-5-(Trifluoromethyl)Benzenesulfonyl Chloride is a high-purity, multi-functional aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique trifluoromethyl and fluorine substituents, which are essential for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used to create novel herbicides and fungicides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental persistence.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and functional materials.
• Chemical Research: Employed as a versatile reagent for introducing the sulfonyl chloride functional group into complex molecular architectures.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized colorants and photographic chemicals.

Basic Information

Product Name	3-Fluoro-4-Methyl-5-(Trifluoromethyl)Benzenesulfonyl Chloride
CAS No.	1706451-99-1
Molecular Formula	C8H5ClF4O2S
Molecular Weight	276.64 g/mol
Synonyms	3-Fluoro-4-methyl-5-(trifluoromethyl)benzene-1-sulfonyl chloride; 5-(Trifluoromethyl)-3-fluoro-4-methylbenzenesulfonyl chloride; 2-Fluoro-1-methyl-6-(trifluoromethyl)benzene-4-sulfonyl chloride; Benzenesulfonyl chloride, 3-fluoro-4-methyl-5-(trifluoromethyl)-; 3-Fluoro-4-methyl-alpha,alpha,α-trifluoro-m-toluenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Methyl-5-(Trifluoromethyl)Benzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.