Description

4-Ethoxy-3-(trifluoromethyl)benzenesulfonyl chloride is a specialized aromatic sulfonyl chloride derivative, a crucial building block in advanced organic synthesis. Its value lies in its dual functional groups, enabling it to act as a versatile electrophile for introducing the sulfonamide moiety into target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in creating sulfonamide-based drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with sulfonamide backbones.
• Material Science Research: Employed in the creation of specialty polymers and functional materials where sulfonamide linkages are required.
• Chemical Biology Probes: Serves as a reagent for modifying proteins or other biomolecules to study biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise sulfonylation reactions.

Basic Information

Product Name	4-Ethoxy-3-(Trifluoromethyl)Benzenesulfonylchloride
CAS No.	1706446-86-7
Molecular Formula	C9H8ClF3O3S
Molecular Weight	288.67 g/mol
Synonyms	4-Ethoxy-3-(trifluoromethyl)benzene-1-sulfonyl chloride; 3-Trifluoromethyl-4-ethoxybenzenesulfonyl chloride; 1-Ethoxy-2-(trifluoromethyl)-4-sulfonylchloridebenzene; 4-Ethoxy-α,α,α-trifluoro-m-toluenesulfonyl chloride; 4-Ethoxy-3-trifluoromethylphenylsulfonyl chloride; ETMBS-Cl; 1706446-86-7
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-3-(trifluoromethyl)benzenesulfonyl chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.