Description

3-Bromo-5-(Trifluoromethoxy)Benzenesulfonylchloride is a high-purity, multi-functional chemical intermediate essential for advanced organic synthesis. Its unique structure, featuring both bromo and sulfonyl chloride functional groups, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated aromatic core.
• Material Science Research: Serves as a precursor for creating specialized polymers, liquid crystals, and other functional materials requiring sulfonyl chloride chemistry.
• Chemical Derivatization: The reactive sulfonyl chloride group enables efficient labeling and modification of other organic compounds for analytical or synthetic purposes.
• Cross-Coupling Reactions: The bromo substituent makes it a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form complex biaryl structures.

Basic Information

Product Name	3-Bromo-5-(Trifluoromethoxy)Benzenesulfonylchloride
CAS No.	1706446-78-7
Molecular Formula	C7H3BrClF3O3S
Molecular Weight	339.51 g/mol
Synonyms	3-Bromo-5-(trifluoromethoxy)benzenesulfonyl chloride; 1-Bromo-3-(trifluoromethoxy)-5-(chlorosulfonyl)benzene; Benzenesulfonyl chloride, 3-bromo-5-(trifluoromethoxy)-; 3-Bromo-α,α,α-trifluoro-5-methoxybenzenesulfonyl chloride; 3-Bromo-5-(trifluoromethoxy)phenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-(Trifluoromethoxy)Benzenesulfonylchloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive R&D and scale-up processes. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.