Description

2,3-Dichloro-6-Fluorobenzenesulfonylchloride is a high-value, multi-functional sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its molecular structure makes it an essential precursor for introducing the benzenesulfonyl moiety into target molecules, enabling the development of compounds with specific biological or material properties. This intermediate is particularly vital for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require precise and reliable synthetic pathways.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the sulfonyl group is integral to biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology & Proteomics: Employed as a reagent for protein labeling and activity-based probe development due to its reactive sulfonyl chloride group.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of complex sulfonated dyes and colorants.
• Custom Synthesis & Contract Manufacturing: A crucial starting material for fine chemical companies offering bespoke synthesis services.

Basic Information

Product Name	2,3-Dichloro-6-Fluorobenzenesulfonylchloride
CAS No.	1706446-66-3
Molecular Formula	C6H2Cl3FO2S
Molecular Weight	267.50 g/mol
Synonyms	2,3-Dichloro-6-fluorobenzenesulfonyl chloride; 2,3-Dichloro-6-fluorobenzene-1-sulfonyl chloride; Benzenesulfonyl chloride, 2,3-dichloro-6-fluoro-; 1-(Chlorosulfonyl)-2,3-dichloro-4-fluorobenzene; 2,3-Dichloro-4-fluorobenzenesulfonyl chloride; 6-Fluoro-2,3-dichlorobenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2,3-Dichloro-6-Fluorobenzenesulfonylchloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA), including results for assay, identity, and impurity profiles (typically by HPLC/GC), is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.