Description

4-Chloro-3,5-Difluorobenzenesulfonylchloride is a high-purity, multi-functional sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual reactive sites, enabling the efficient introduction of the sulfonyl group and facilitating further functionalization, which is essential for creating complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Used in the production of specialty polymers, dyes, and liquid crystals where sulfonyl groups impart specific thermal or optical properties.
• Chemical Research: Versatile reagent for introducing the benzenesulfonyl moiety in medicinal chemistry and process optimization studies.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing tailored compounds for client projects.

Basic Information

Product Name	4-Chloro-3,5-Difluorobenzenesulfonylchloride
CAS No.	1706435-19-9
Molecular Formula	C6H2Cl2F2O2S
Molecular Weight	247.04 g/mol
Synonyms	4-Chloro-3,5-difluorobenzenesulfonyl chloride; 3,5-Difluoro-4-chlorobenzenesulfonyl chloride; 1-Chloro-2,6-difluoro-4-sulfonylchloridebenzene; Benzenesulfonyl chloride, 4-chloro-3,5-difluoro-; 4-Chloro-3,5-difluorophenylsulfonyl chloride; 2,6-Difluoro-4-chlorobenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Chloro-3,5-Difluorobenzenesulfonylchloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.