Description

4-Methoxy-3-Methyl-5-(Trifluoromethyl)Benzenesulfonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive sulfonyl chloride group and trifluoromethyl substituent. This compound is critical for introducing the sulfonamide moiety into target molecules, a key step in the synthesis of advanced materials and bioactive compounds. It is primarily sought after by research and development teams, process chemists, and manufacturers in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Serves as a precursor for functional polymers, dyes, and liquid crystals, leveraging its aromatic and sulfonyl chloride reactivity.
• Chemical Research: Employed in academic and industrial R&D for exploring new organic reactions and creating specialized chemical libraries.
• Custom Synthesis: A vital starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	4-Methoxy-3-Methyl-5-(Trifluoromethyl)Benzenesulfonyl Chloride
CAS No.	1706435-16-6
Molecular Formula	C9H8ClF3O3S
Molecular Weight	288.67 g/mol
Synonyms	3-Methyl-4-methoxy-5-(trifluoromethyl)benzenesulfonyl chloride; 5-(Trifluoromethyl)-4-methoxy-3-methylbenzenesulfonyl chloride; 4-Methoxy-3-methyl-α,α,α-trifluoro-m-toluenesulfonyl chloride; 1-Methoxy-2-methyl-6-(trifluoromethyl)-4-benzenesulfonyl chloride; 2-Methyl-1-methoxy-3-(trifluoromethyl)-5-benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Methoxy-3-Methyl-5-(Trifluoromethyl)Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.