Description

4-Chloro-2-Fluoro-3-Methoxybenzenesulfonyl Chloride is a high-purity, multi-functional chemical intermediate essential for advanced organic synthesis. Its value lies in its reactive sulfonyl chloride group and strategically placed halogen and methoxy substituents, enabling precise molecular construction. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides, leveraging its halogenated aromatic structure.
• Material Science Research: Serves as a precursor for functionalized polymers and advanced materials requiring specific sulfonyl groups.
• Chemical Biology Probes: Employed in creating activity-based probes and affinity labels for studying enzyme function.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, halogenated benzenesulfonyl derivatives.

Basic Information

Product Name	4-Chloro-2-Fluoro-3-Methoxybenzenesulfonyl Chloride
CAS No.	1706435-13-3
Molecular Formula	C7H5Cl2FO3S
Molecular Weight	283.08 g/mol
Synonyms	3-Methoxy-4-chloro-2-fluorobenzenesulfonyl chloride; 4-Chloro-2-fluoro-3-methoxybenzene-1-sulfonyl chloride; 1-Chlorosulfonyl-4-chloro-2-fluoro-3-methoxybenzene; 2-Fluoro-3-methoxy-4-chlorobenzenesulfonyl chloride; Benzenesulfonyl chloride, 4-chloro-2-fluoro-3-methoxy-; CAS 1706435-13-3
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluoro-3-Methoxybenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.