Description

2-Fluoro-5-Methyl-4-(Trifluoromethyl)Benzenesulfonyl Chloride is a high-value, multi-functional chemical building block essential for advanced organic synthesis. Its core value lies in its role as a versatile sulfonylation reagent, enabling the precise introduction of a complex, fluorinated aryl sulfonyl group into target molecules. This compound is critically needed by R&D and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, particularly where enhanced metabolic stability and lipophilicity are desired.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Serves as a precursor for creating specialty polymers and advanced materials with unique surface properties.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying enzyme function and mechanism.
• Ligand and Catalyst Development: Utilized to construct complex, fluorinated ligands for catalysis and molecular recognition applications.

Basic Information

Product Name	2-Fluoro-5-Methyl-4-(Trifluoromethyl)Benzenesulfonyl Chloride
CAS No.	1706431-05-1
Molecular Formula	C9H5ClF4O2S
Molecular Weight	296.65 g/mol
Synonyms	2-Fluoro-5-methyl-4-(trifluoromethyl)benzenesulfonyl chloride; 4-(Trifluoromethyl)-2-fluoro-5-methylbenzenesulfonyl chloride; 2-Fluoro-α,α,α-trifluoro-5-methyl-p-toluenesulfonyl chloride; 2-Fluoro-5-methyl-4-trifluoromethylbenzenesulfonyl chloride; 1706431-05-1; 4-(Trifluoromethyl)-2-fluoro-5-methylbenzene-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methyl-4-(Trifluoromethyl)Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.