Description

1-(Chloromethyl)-3-(difluoromethyl)-5-(trifluoromethyl)benzene is a highly functionalized aromatic building block containing multiple halogen substituents. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, particularly in the development of complex molecules. It is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical industries for creating active ingredients and specialty materials. The specific reactivity of its chloromethyl and fluorinated methyl groups makes it a critical precursor for introducing specific functionalities into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where fluorination improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Incorporated as a monomer or cross-linking agent to impart specific chemical resistance and thermal properties to specialty polymers.
• Organic Synthesis Reagent: Employed in medicinal chemistry and material science research for constructing complex, multi-functional aromatic scaffolds.

Basic Information

Product Name	1-(Chloromethyl)-3-(difluoromethyl)-5-(trifluoromethyl)benzene
CAS No.	1705894-30-9
Molecular Formula	C9H6ClF5
Molecular Weight	244.59 g/mol
Synonyms	3-(Chloromethyl)-α,α,α,5-tetrafluoro-m-xylene; 1-Chloromethyl-3-difluoromethyl-5-trifluoromethylbenzene; 3-(Difluoromethyl)-5-(trifluoromethyl)benzyl chloride; α,α,α,5-Tetrafluoro-3-(chloromethyl)toluene; 3-(Chloromethyl)-α,α,α,5-tetrafluorotoluene; (3-(Difluoromethyl)-5-(trifluoromethyl)phenyl)methanol chloride
EINECS	Contact for details

Quality Control

Our 1-(Chloromethyl)-3-(difluoromethyl)-5-(trifluoromethyl)benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. Handle and store under an inert atmosphere if prolonged storage is required to maintain optimal quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.