Description

(4-(N,N-Dimethylsulfamoyl)Naphthalen-1-Yl)Boronic Acid is a high-value, functionalized naphthalene boronic acid derivative designed for advanced organic synthesis. This compound is a critical building block in modern pharmaceutical and materials science research, enabling the construction of complex molecules through efficient cross-coupling reactions. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel sulfonamide-containing target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing potential drug candidates, particularly those containing a naphthalene-sulfonamide pharmacophore.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by introducing the dimethylsulfamoyl-naphthalene moiety into lead structures.
• Material Science: Serves as a monomer or functionalizing agent in the synthesis of organic electronic materials, such as polymers for OLEDs or sensors.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes and enzyme inhibitors that target sulfonamide-binding proteins.
• Ligand Synthesis: Useful for creating novel bidentate or tridentate ligands for catalysis, leveraging the boronic acid and sulfonamide functional groups.
• Library Synthesis: A valuable building block for generating diverse compound libraries in high-throughput screening and medicinal chemistry programs.

Basic Information

Product Name	(4-(N,N-Dimethylsulfamoyl)Naphthalen-1-Yl)Boronic Acid
CAS No.	1704097-52-8
Molecular Formula	C₁₂H₁₄BNO₄S
Molecular Weight	279.12 g/mol
Synonyms	4-(Dimethylsulfamoyl)-1-naphthaleneboronic Acid; 1-Borono-4-(N,N-dimethylsulfamoyl)naphthalene; (4-Dimethylsulfamoylnaphthalen-1-yl)boronic Acid; B-[4-(Dimethylsulfamoyl)-1-naphthyl]boronic Acid; 1704097-52-8; 4-(N,N-Dimethylsulfamoyl)-1-naphthaleneboronic Acid; 4-(Dimethylaminosulfonyl)-1-naphthaleneboronic Acid
EINECS	Contact for details

Quality Control

Our (4-(N,N-Dimethylsulfamoyl)Naphthalen-1-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.