Description

Gsk-3 β Inhibitor 2 CAS NO 1702428-31-6 is a potent and selective small molecule inhibitor of glycogen synthase kinase-3 beta (GSK-3β), a serine/threonine kinase involved in numerous critical cellular signaling pathways. This compound is a vital research tool for investigating the role of GSK-3β in diseases such as neurological disorders, diabetes, and cancer. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in drug discovery and molecular biology studies.

Application

• Biochemical Research: A key reagent for in vitro enzymatic assays to study GSK-3β kinase activity and inhibition kinetics.
• Cell-Based Studies: Used to probe Wnt/β-catenin, insulin, and other signaling pathways in cultured cell lines to understand disease mechanisms.
• Drug Discovery & Development: Serves as a reference compound or lead molecule in high-throughput screening (HTS) campaigns and structure-activity relationship (SAR) studies for novel therapeutics.
• Neuroscience Research: Investigated for its potential neuroprotective effects in models of Alzheimer's disease, bipolar disorder, and other CNS conditions.
• Metabolic Disease Research: Applied in studies focusing on insulin resistance, glucose metabolism, and type 2 diabetes.
• Oncology Research: Explored for its role in modulating apoptosis and cell proliferation in various cancer cell models.

Basic Information

Item	Detail
Product Name	Gsk-3 β Inhibitor 2
CAS No.	1702428-31-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GSK-3β Inhibitor 2; GSK-3β Inhibitor II; GSK-3β Inhibitor 2 (CAS 1702428-31-6); GSK-3β Inhibitor; Glycogen Synthase Kinase-3 Beta Inhibitor 2; 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile; (S)-6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-4,5-dihydro-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile
EINECS	Contact for details

Quality Control

Our Gsk-3 β Inhibitor 2 is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. All materials are characterized using advanced analytical techniques, including NMR and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment to support your research documentation and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccated conditions. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and potency. Allow the vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.