Description

2,3-Difluoro-4-Methylbenzenesulfonylchloride is a high-purity, reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce the sulfonamide functional group, a key motif in the development of active pharmaceutical ingredients and specialty agrochemicals. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the sulfonamide group enhances biological activity.
• Material Science: Employed in the creation of specialty polymers and functional materials that require sulfonamide linkages for specific properties.
• Chemical Research & Development: Serves as a versatile reagent for introducing sulfonyl groups in medicinal chemistry and process optimization studies.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized sulfonated colorants.

Basic Information

Item	Details
Product Name	2,3-Difluoro-4-Methylbenzenesulfonylchloride
CAS No.	1698682-03-9
Molecular Formula	C7H5ClF2O2S
Molecular Weight	226.63 g/mol
Synonyms	2,3-Difluoro-4-methylbenzenesulfonyl chloride; 4-Methyl-2,3-difluorobenzenesulfonyl chloride; 2,3-Difluoro-p-toluenesulfonyl chloride; 2,3-Difluoro-4-methylbenzene-1-sulfonyl chloride; 1-(Chlorosulfonyl)-2,3-difluoro-4-methylbenzene; 2,3-Difluoro-4-methylphenylsulfonyl chloride; 2,3-Difluoro-4-toluenesulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2,3-Difluoro-4-Methylbenzenesulfonylchloride is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the high standards required for research and industrial synthesis. Our quality control protocols include identity confirmation, purity assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.