Description

Brd4 Inhibitor-10 CAS NO 1660117-38-3 is a potent and selective small molecule inhibitor targeting the Bromodomain and Extra-Terminal (BET) protein BRD4. This compound matters for its crucial role in disrupting protein-protein interactions involved in transcriptional regulation, offering a powerful tool for epigenetic research and therapeutic development. It is primarily needed by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in oncology, immunology, and inflammatory disease research.

Application

• Epigenetics and Transcriptional Regulation Research: Used as a key pharmacological probe to study the role of BRD4 and BET proteins in gene expression control.
• Oncology Drug Discovery: Investigated for its potential to inhibit the growth of cancer cells, particularly in hematological malignancies and solid tumors driven by oncogenic transcription.
• Inflammatory and Autoimmune Disease Models: Applied in preclinical studies to evaluate the modulation of inflammatory pathways and cytokine production.
• Chemical Biology and Target Validation: Serves as a reference compound for developing assays, understanding structure-activity relationships (SAR), and validating BRD4 as a therapeutic target.
• Combination Therapy Studies: Explored in conjunction with other therapeutic agents, such as kinase inhibitors or immunomodulators, to assess synergistic effects.

Basic Information

Item	Details
Product Name	Brd4 Inhibitor-10
CAS No.	1660117-38-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	BRD4 Inhibitor-10; 1660117-38-3; BRD4 Inhibitor 10; (S)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate; UNII-6V6B5BQ9QY; CHEMBL2103875; BDBM50380857; HY-12465
EINECS	Contact for details

Quality Control

Our Brd4 Inhibitor-10 is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing identity, purity, and assay results is provided with every shipment to support your research integrity and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95%
Water Content	≤1.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.