Description

(Ack1 Inhibitor (R)-9B) is a potent and selective small molecule inhibitor targeting the Activated Cdc42-associated kinase 1 (Ack1/TNK2), a non-receptor tyrosine kinase implicated in various oncogenic signaling pathways. This high-purity compound is essential for biochemical and cellular research, enabling the study of cancer cell proliferation, survival, and metastasis. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on oncology drug discovery and signal transduction research.

Application

• Biochemical Research: Used as a selective tool compound for in vitro kinase assays to study Ack1 inhibition kinetics and mechanism of action.
• Cellular Biology Studies: Applied in cell culture models to investigate the role of Ack1 in cancer cell signaling, proliferation, and apoptosis.
• Preclinical Drug Discovery: Serves as a key reference standard and lead compound in the development of novel oncology therapeutics targeting tyrosine kinases.
• Pathway Analysis: Utilized to delineate the Ack1 signaling axis in diseases such as prostate cancer, breast cancer, and non-small cell lung cancer (NSCLC).
• High-Throughput Screening (HTS): Employed as a control or validation compound in screening campaigns for identifying new Ack1 inhibitors.

Basic Information

Product Name	(Ack1 Inhibitor (R)-9B)
CAS No.	1655527-68-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(R)-9B; Ack1 Inhibitor R-9B; (R)-Ack1 Inhibitor 9B; TNK2 Inhibitor (R)-9B; Activated CDC42 kinase 1 inhibitor (R)-9B; Potential research compound names based on structure.
EINECS	Contact for details

Quality Control

Our (Ack1 Inhibitor (R)-9B) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider storing under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.