Description

6-(Difluoromethyl)Pyridin-3-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and organic building block. This compound is valued for its unique difluoromethylated pyridine core, which is critical for modulating the physicochemical and metabolic properties of target molecules in drug discovery. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance biological activity and stability.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of complex molecular architectures in medicinal and synthetic chemistry.
• Material Science: Potential application in the development of advanced organic materials, including ligands for catalysis and components for electronic materials.

Basic Information

Item	Details
Product Name	6-(Difluoromethyl)Pyridin-3-Amine Hydrochloride
CAS No.	1646152-50-2
Molecular Formula	C6H7ClF2N2
Molecular Weight	180.58 g/mol
Synonyms	3-Amino-6-(difluoromethyl)pyridine hydrochloride; 6-(Difluoromethyl)-3-pyridinamine hydrochloride; 6-(Difluoromethyl)pyridin-3-amine HCl; 5-Amino-2-(difluoromethyl)pyridine hydrochloride; 2-(Difluoromethyl)-5-aminopyridine hydrochloride; 3-Pyridinamine, 6-(difluoromethyl)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 6-(Difluoromethyl)Pyridin-3-Amine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.