Description

4,6-Difluoropyridin-3-Amine CAS NO 1643855-24-6 is a high-purity fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique difluoro-substituted amine structure, which is essential for modulating the electronic and steric properties of target molecules. This intermediate is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, including potential drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial labs for method development and the creation of novel chemical libraries for screening.
• Fluorinated Compound Manufacturing: Acts as a versatile starting material for the preparation of more complex, multi-fluorinated heterocyclic compounds.

Basic Information

Product Name	4,6-Difluoropyridin-3-Amine
CAS No.	1643855-24-6
Molecular Formula	C5H4F2N2
Molecular Weight	130.10 g/mol
Synonyms	3-Amino-4,6-difluoropyridine; 4,6-Difluoro-3-pyridinamine; 4,6-Difluoropyridin-3-ylamine; 4,6-Difluoro-3-aminopyridine; 3-Pyridinamine, 4,6-difluoro-; 1643855-24-6
EINECS	Contact for details

Quality Control

Our 4,6-Difluoropyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ISO, and other relevant quality standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.