Description

Pde1-In-1 (Phosphate) is a high-purity, small molecule inhibitor specifically targeting phosphodiesterase 1 (PDE1). This compound is a critical research tool for investigating cyclic nucleotide signaling pathways and their role in cellular physiology. It is primarily utilized by pharmaceutical R&D teams and academic researchers in the fields of neuroscience, cardiology, and oncology for target validation and early-stage drug discovery.

Application

• Biochemical Research: Used as a selective inhibitor to study the function and regulation of PDE1 isoforms in in vitro enzyme assays.
• Cellular Signaling Studies: Applied in cell-based models to elucidate the role of PDE1 in cyclic AMP (cAMP) and cyclic GMP (cGMP) mediated pathways.
• Neuroscience & Neuropharmacology: Investigated for its potential effects on neuronal function, synaptic plasticity, and in models of neurodegenerative diseases.
• Cardiovascular Research: Explored for modulating vascular tone and cardiac function through PDE1 inhibition in relevant tissue and animal models.
• Preclinical Drug Development: Serves as a reference compound or lead molecule for developing novel therapeutics targeting PDE1-associated disorders.
• High-Throughput Screening (HTS): Employed as a control or validation compound in screening campaigns to identify new PDE1 modulators.

Basic Information

Product Name	Pde1-In-1 (Phosphate)
CAS No.	1642303-38-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PDE1 Inhibitor 1 (phosphate salt); PDE1-IN-1 phosphate; Phosphodiesterase 1 Inhibitor 1 phosphate; 1642303-38-5; PDE1i-1 (phosphate); Pde1-In-1 phosphate salt; Research compound 1642303-38-5
EINECS	Contact for details

Quality Control

Our Pde1-In-1 (Phosphate) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectral confirmation (NMR, MS) for structural identity, to ensure consistency and reliability for research applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C. Allow the product to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤5.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.