Description

σ-1 Receptor Antagonist 2 CAS NO 1639220-15-7 is a high-purity, small-molecule research chemical designed for selective inhibition of the σ-1 receptor. This compound is a critical tool for neuroscientific and pharmacological research, enabling the study of neuropathic pain, neurodegenerative disorders, and psychiatric conditions. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and contract research organizations (CROs) focused on central nervous system (CNS) drug discovery and mechanism-of-action studies.

Application

• Neuroscience Research: Investigation of σ-1 receptor function and its role in pain modulation, neuroprotection, and neuroplasticity.
• Drug Discovery & Development: Serving as a reference standard, pharmacological tool, or lead compound in CNS-targeted pharmaceutical R&D pipelines.
• In Vitro & In Vivo Studies: Utilization in cell-based assays and animal models to evaluate efficacy, pharmacokinetics, and toxicology profiles for potential therapeutics.
• Psychiatric Disorder Research: Exploring pathways related to depression, anxiety, schizophrenia, and addiction where σ-1 receptors are implicated.
• Neurodegenerative Disease Models: Research into conditions such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS).
• Biochemical Pathway Analysis: Use in signal transduction studies to elucidate downstream effects of σ-1 receptor antagonism.

Basic Information

Item	Detail
Product Name	σ-1 Receptor Antagonist 2
CAS No.	1639220-15-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	σ-1 Receptor Antagonist 2; S1RA Analog; σ-1 Antagonist; SR Antagonist; CNS Research Compound 1639220-15-7; Neuropharmacological Research Agent; σ-1 Receptor Blocker
EINECS	Contact for details

Quality Control

Our σ-1 Receptor Antagonist 2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.