Description

2-Fluoro-6-Isopropoxypyridine-3-Boronic Acid is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing pyridine-based scaffolds in drug discovery and development, particularly for kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific fluorinated heterocyclic structures.
• Material Science: Serves as a precursor for creating functionalized ligands, organic electronic materials, and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: Primarily employed in Suzuki-Miyaura cross-coupling with aryl/heteroaryl halides to form biaryl and heterobiaryl linkages efficiently.
• Chemical Biology Probes: Utilized in the synthesis of tagged molecules and probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring specific fluorinated boronic acid derivatives.

Basic Information

Product Name	2-Fluoro-6-Isopropoxypyridine-3-Boronic Acid
CAS No.	1637749-71-3
Molecular Formula	C9H13BFNO3
Molecular Weight	213.02 g/mol
Synonyms	(2-Fluoro-6-isopropoxypyridin-3-yl)boronic acid; 2-Fluoro-6-(propan-2-yloxy)pyridine-3-boronic acid; 3-Borono-2-fluoro-6-isopropoxypyridine; 2-Fluoro-6-isopropoxy-3-pyridineboronic acid; 1637749-71-3; B-(2-Fluoro-6-isopropoxy-3-pyridinyl)boronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-Isopropoxypyridine-3-Boronic Acid is produced and tested under strict quality management protocols. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); therefore, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.