Description

(3R,5R,8R,9R,10S,13S,14S)-3-Hydroxy-3,13-Dimethyltetradecahydro-1H-Cyclopenta[A]Phenanthren-17(2H)-One (Wx116161) is a high-purity, stereochemically defined steroid derivative with the CAS number 1632051-92-3. This compound serves as a critical advanced intermediate or reference standard in the research and development of novel pharmaceutical agents, particularly in the fields of endocrinology and oncology. It is essential for scientists and manufacturers requiring a structurally precise building block for synthesizing complex bioactive molecules or for use in analytical method development and validation.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel steroid-based therapeutics and hormone analogs.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control (QC) of related steroid compounds.
• Biochemical Research: Employed in academic and industrial R&D to study steroid receptor interactions, metabolic pathways, and enzyme inhibition.
• Process Development: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Custom Synthesis: A foundational compound for the contract manufacturing of specialized, high-value fine chemicals and labeled isotopes.

Basic Information

Product Name	(3R,5R,8R,9R,10S,13S,14S)-3-Hydroxy-3,13-Dimethyltetradecahydro-1H-Cyclopenta[A]Phenanthren-17(2H)-One (Wx116161)
CAS No.	1632051-92-3
Molecular Formula	C19H30O2
Molecular Weight	290.44 g/mol
Synonyms	Wx116161; 3β-Hydroxy-5α-androstan-17-one (specific stereoisomer); 17-Keto-5α-androstane-3β-ol; Dihydrotestosterone-related intermediate; Androstane-3β,17-diol 17-one; 5α-Androstan-3β-ol-17-one; (3β,5α,8α,9β,10α,13α,14β)-3-Hydroxy-3,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-one
EINECS	Contact for details

Quality Control

Every batch of (3R,5R,8R,9R,10S,13S,14S)-3-Hydroxy-3,13-Dimethyltetradecahydro-1H-Cyclopenta[A]Phenanthren-17(2H)-One is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral purity verification, to ensure compliance with stringent industry standards for research and pharmaceutical intermediates. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (by chiral HPLC)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.