Description

Pd-1/Pd-L1 Inhibitor 4 CAS NO 1629655-94-2 is a potent and selective small molecule inhibitor targeting the PD-1/PD-L1 immune checkpoint pathway. This compound is critical for advancing research and development in immuno-oncology, offering a tool to modulate T-cell activity and overcome tumor-mediated immune suppression. It is primarily needed by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on developing next-generation cancer immunotherapies and combination treatment strategies.

Application

• Immuno-oncology Research: Fundamental tool for studying the PD-1/PD-L1 signaling axis in vitro and in vivo.
• Drug Discovery & Development: Serves as a reference compound or lead structure for designing novel immune checkpoint inhibitors.
• Preclinical Studies: Used in animal models to evaluate the efficacy of PD-1/PD-L1 blockade in various cancer types.
• Mechanistic Biology: Enables investigation of tumor immune evasion mechanisms and T-cell exhaustion.
• Combination Therapy Research: Explored in studies combining checkpoint inhibition with chemotherapy, radiotherapy, or other immunomodulators.
• Biomarker Development: Aids in correlating pathway inhibition with therapeutic response in research settings.

Basic Information

Product Name	Pd-1/Pd-L1 Inhibitor 4
CAS No.	1629655-94-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PD-1/PD-L1 Inhibitor 4; BMS-8; BMS-8 (PD-1/PD-L1 inhibitor); (S)-1-((2-(4-Chlorophenyl)-4-((4-((4-fluorophenyl)carbamoyl)piperidin-1-yl)methyl)thiazol-5-yl)methyl)-5-fluoropyrrolidine-2-carboxamide; UNII-9K5J0QDK0P; 9K5J0QDK0P; BMS-8 immune checkpoint inhibitor
EINECS	Contact for details

Quality Control

Our Pd-1/Pd-L1 Inhibitor 4 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This compound is hygroscopic (moisture-sensitive) and must be handled in a dry environment to maintain stability and potency. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.