Description

Integrin Antagonist 1 (Hydrochloride) is a potent and selective small molecule inhibitor designed for advanced research applications. This compound is critical for investigating cell adhesion, migration, and signaling pathways mediated by integrin receptors. It is primarily utilized by pharmaceutical R&D teams and academic researchers in the fields of oncology, fibrosis, and inflammatory disease studies.

Application

• Biomedical Research: A key tool compound for in vitro and in vivo studies targeting integrin-mediated processes in cancer metastasis and angiogenesis.
• Drug Discovery & Development: Serves as a reference standard and pharmacological probe in high-throughput screening and lead optimization programs.
• Mechanistic Studies: Used to elucidate the role of specific integrins in cellular signaling cascades, apoptosis, and proliferation.
• Preclinical Modeling: Essential for validating therapeutic hypotheses and establishing proof-of-concept in animal models of disease.

Basic Information

Product Name	Integrin Antagonist 1 (Hydrochloride)
CAS No.	1629249-40-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Integrin Antagonist 1 HCl; (S)-2-(4-Fluorobenzyl)-5,7-dihydroxy-8-((S)-1-hydroxypropan-2-yl)-4-oxo-4H-chromene-6-carboxylic acid hydrochloride; CAS 1629249-40-6; αVβ3 Integrin Antagonist; RGD mimetic hydrochloride salt; Cell adhesion inhibitor 1 (HCl)
EINECS	Contact for details

Quality Control

Our Integrin Antagonist 1 (Hydrochloride) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccated conditions. The product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.