Description

2-Fluoro-5-(Methoxycarbonyl)Pyridine-3-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate belonging to the class of pyridine boronic acid pinacol esters. This compound is a critical building block in modern organic synthesis, valued for its role in facilitating efficient carbon-carbon bond formation. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl structures prevalent in drug discovery.
• Pharmaceutical Intermediate: Serves as a versatile precursor in the synthesis of complex molecules targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Potential building block for creating functional organic materials and ligands for catalysis.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for biological studies.

Basic Information

Product Name	2-Fluoro-5-(Methoxycarbonyl)Pyridine-3-Boronic Acid Pinacol Ester
CAS No.	1622217-36-0
Molecular Formula	C14H19BFNO4
Molecular Weight	295.12 g/mol
Synonyms	3-Borono-2-fluoro-5-(methoxycarbonyl)pyridine pinacol ester; (2-Fluoro-5-(methoxycarbonyl)pyridin-3-yl)boronic acid pinacol ester; 5-Methoxycarbonyl-2-fluoropyridine-3-boronic acid pinacol ester; 2-Fluoro-5-methoxycarbonylpyridine-3-boronic acid pinacol ester; Pinacol 2-fluoro-5-(methoxycarbonyl)pyridine-3-boronate; CAS 1622217-36-0
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-(Methoxycarbonyl)Pyridine-3-Boronic Acid Pinacol Ester is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.