Description

2-[(Difluoroiodomethyl)Sulfonyl]-Pyridine is a specialized organoiodine and sulfone reagent designed for advanced synthetic chemistry applications. This compound is valued for its unique reactivity profile, enabling the introduction of difluoroiodomethylsulfonyl groups into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in medicinal chemistry and material science research.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring fluorinated or sulfonated motifs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the difluoroiodomethylsulfonyl moiety can enhance biological activity and metabolic stability.
• Material Science: Serves as a precursor for functionalized polymers and advanced materials with specific electronic or surface properties.
• Cross-Coupling Reagent: Acts as an electrophilic coupling partner in transition metal-catalyzed reactions for carbon-heteroatom bond formation.
• Fluorination Agent: Utilized as a source of the difluoromethyl group in radical or nucleophilic fluorination reactions.
• Sulfonyl Transfer Reagent: Enables the direct sulfonylation of various nucleophiles in organic synthesis.

Basic Information

Item	Details
Product Name	2-[(Difluoroiodomethyl)Sulfonyl]-Pyridine
CAS No.	1621689-73-3
Molecular Formula	C7H5F2INO2S
Molecular Weight	315.09 g/mol
Synonyms	Pyridine, 2-[(difluoroiodomethyl)sulfonyl]-; 2-(Difluoroiodomethylsulfonyl)pyridine; 2-Pyridyl difluoroiodomethyl sulfone; (Difluoroiodomethyl)sulfonyl pyridine; DFIMSP
EINECS	Contact for details

Quality Control

Our 2-[(Difluoroiodomethyl)Sulfonyl]-Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.