Description

Ethyl 2-(5-Bromo-3-Fluoropyridin-2-Yl)Acetate is a high-purity fluorinated pyridine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated pyridine motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides that require fluorinated pyridine cores for enhanced bioactivity and environmental profile.
• Material Science Research: Employed in the creation of organic ligands for catalysis and as a precursor for functionalized materials, including liquid crystals and organic semiconductors.
• Chemical Biology Probes: Serves as a versatile handle for creating fluorescent tags, affinity probes, and other tools for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	Ethyl 2-(5-Bromo-3-Fluoropyridin-2-Yl)Acetate
CAS No.	1620318-88-8
Molecular Formula	C9H9BrFNO2
Molecular Weight	262.08 g/mol
Synonyms	Ethyl (5-Bromo-3-fluoropyridin-2-yl)acetate; 2-(5-Bromo-3-fluoro-2-pyridinyl)acetic acid ethyl ester; Acetic acid, 2-(5-bromo-3-fluoro-2-pyridinyl)-, ethyl ester; 5-Bromo-3-fluoro-2-pyridineacetic acid ethyl ester; Ethyl 5-bromo-3-fluoro-2-pyridylacetate; 1620318-88-8; Ethyl (5-bromo-3-fluoropyridin-2-yl)acetate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(5-Bromo-3-Fluoropyridin-2-Yl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.