Description

3-Bromo-4,5-difluoropyridine is a high-purity, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its precise molecular architecture, featuring bromine and fluorine substituents, enables selective functionalization and is essential for constructing complex pharmacophores and agrochemicals. This compound is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized nitrogen-containing ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the creation of novel organic electronic materials, such as charge-transport layers and fluorinated polymers.
• Chemical Biology Probes: Utilized as a versatile handle for labeling and modifying biomolecules in probe and diagnostic reagent development.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.

Basic Information

Product Name	3-Bromo-4,5-difluoropyridine
CAS No.	1613198-18-7
Molecular Formula	C5H2BrF2N
Molecular Weight	193.98 g/mol
Synonyms	4,5-Difluoro-3-bromopyridine; 3-Bromo-4,5-difluoropyridine; Pyridine, 3-bromo-4,5-difluoro-; 1613198-18-7; 3-Br-4,5-F2-Py
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4,5-difluoropyridine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates and ISO standards for industrial chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong alkali and fluoride ions; keep away from incompatible materials. Keep container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.