Description

(E)-Gabab Receptor Antagonist 1 is a high-purity, small-molecule research chemical designed for advanced neuroscience and pharmacological studies. This compound serves as a potent and selective tool for investigating the structure and function of GABAB receptors, which are critical targets in neurological and psychiatric disorder research. It is essential for pharmaceutical R&D, academic research, and contract research organizations (CROs) focused on developing novel therapeutics for conditions like anxiety, depression, and addiction.

Application

• Neuroscience Research: A key pharmacological tool for studying GABAB receptor signaling pathways, neuronal excitability, and synaptic transmission.
• Drug Discovery & Development: Used in high-throughput screening (HTS) and lead optimization programs targeting CNS disorders.
• Biochemical Assays: Employed as a reference standard in receptor binding studies, functional cellular assays, and enzyme inhibition tests.
• Academic & Institutional Research: Supports fundamental research in universities and institutes exploring neuropharmacology and neurochemistry.
• Preclinical Studies: Utilized in animal model research to elucidate the in vivo role of GABAB receptors and evaluate therapeutic potential.
• Chemical Biology: Serves as a molecular probe for target validation and mechanistic studies within complex biological systems.

Basic Information

Product Name	(E)-Gabab Receptor Antagonist 1
CAS No.	1611483-29-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GABAB Receptor Antagonist 1 (E-isomer); (E)-GABA B Antagonist 1; Gabab Antagonist 1; GABA-BR Antagonist 1; Research Compound 1611483-29-4; BGP-788; (E)-selective GABAB antagonist
EINECS	Contact for details

Quality Control

Every batch of (E)-Gabab Receptor Antagonist 1 is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant research-grade standards. Our quality commitment ensures reliable and reproducible results for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. For short-term use, the material may be stored at 2-8°C. The compound is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.