Description

Mito-Tempo CAS NO 1569257-94-8 is a specialized, cell-permeable nitroxide antioxidant designed to target mitochondria. This compound is critical for researchers investigating oxidative stress and mitochondrial function in cellular and animal models. It is primarily utilized in life science research, pharmaceutical development, and biochemical studies focused on aging, neurodegeneration, and metabolic disorders.

Application

• Mitochondrial Research: As a targeted antioxidant to study reactive oxygen species (ROS) generation and scavenging specifically within mitochondria.
• Neurodegenerative Disease Models: Investigation of neuroprotective mechanisms in studies related to Parkinson's, Alzheimer's, and other oxidative stress-related conditions.
• Cardiovascular Research: Examination of mitochondrial dysfunction and oxidative damage in models of ischemia-reperfusion injury and heart failure.
• Aging and Longevity Studies: Used to probe the role of mitochondrial ROS in cellular senescence and aging processes.
• Metabolic Disorder Research: Application in studies of insulin resistance, diabetes, and obesity where mitochondrial oxidative stress is a key factor.
• Pharmaceutical Screening: Serves as a reference compound or tool in high-throughput assays for drug discovery targeting mitochondrial health.
• Biochemical Assay Development: Used as a standard or probe in developing assays for superoxide and other radical species.

Basic Information

Product Name	Mito-Tempo
CAS No.	1569257-94-8
Molecular Formula	C₂₅H₄₅N₂O₃P⁺
Molecular Weight	452.62 g/mol
Synonyms	(2,2,6,6-Tetramethylpiperidin-1-oxyl-4-yl)methyltriphenylphosphonium; MitoTEMPO; Mito-TEMPO; 4-((2,2,6,6-Tetramethylpiperidin-1-oxyl-4-yl)methoxy)-4-oxobutyl)triphenylphosphonium; Mitochondria-targeted TEMPO; TPPMito-TEMPO
EINECS	Contact for details

Quality Control

Our Mito-Tempo is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Orange to red powder or solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, Ethanol; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.