Description

3-Methoxypyridine-2-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the 3-methoxy-2-pyridylsulfonyl moiety into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key reagent for synthesizing sulfonamide-based drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling proteins or modifying biomolecules in probe development and activity-based protein profiling (ABPP).
• Material Science Precursor: Building block for creating functional polymers, ligands for metal-organic frameworks (MOFs), and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for use in custom synthesis projects and scale-up processes.
• Research & Development: Fundamental reagent in academic and industrial R&D labs for exploring new chemical reactions and synthesizing complex heterocyclic compounds.

Basic Information

Item	Detail
Product Name	3-Methoxypyridine-2-Sulfonyl Chloride
CAS No.	1565051-56-0
Molecular Formula	C6H6ClNO3S
Molecular Weight	207.63 g/mol
Synonyms	2-Pyridinesulfonyl chloride, 3-methoxy-; 3-Methoxy-2-pyridinesulfonyl chloride; 3-Methoxypyridine-2-sulfonyl chloride; 3-Methoxy-pyridine-2-sulfonyl chloride; 2-(Chlorosulfonyl)-3-methoxypyridine; 3-Methoxypyridine-2-sulphonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Methoxypyridine-2-Sulfonyl Chloride is manufactured and tested under strict quality management systems. We ensure high purity and batch-to-batch consistency through comprehensive analytical protocols, including HPLC, NMR, and GC-MS. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.